首頁 > 試劑耗材 > Gadospin F MRI動脈粥樣硬化成像造影劑

GadoSpin F是針對動脈粥樣硬化開發的MRI造影劑。它包含了疏水部分用于蛋白結合。該造影劑有效的累積在動脈硬化斑塊處,能夠直接用于T1加權成像。

Gadospin F.jpg 

(右圖)MRI(TFL IR ,1.5T)T1加權成像,在6小時和24小時注射GadoSpin F后,兔子動脈粥樣硬化斑塊檢測。

(左圖):T1 加權MRI成像, GadoSin F高分辨率小鼠血管成像。


參考文獻

1. Zheng, J.et al.(2008) Targeted contrast agent helps to monitor advanced plague during progressiona magnetic resonance imaging study in rabbits. Invest. Radiol. 43:49-55.

2. Raatschen, H.J.et al (2006) MR1 tumor characterization using Gd-GlyMe-DOTA-perfluofooctyl-mannose conjugate (Gadofluorine M), a protein-avid contrast agent. Contrast Media Mol. Imaging 1:113-120.

3. Barkhausen, J.et al (2003) Deteaion of atherosclerotic plaque with Gadofluorine-enhanced magnetic resonance imaging. Circulation 108:605-609.



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